Semipermeable Cellulose Beads Allow Selective and Continuous Release of Small Extracellular Vesicles (sEV) From Encapsulated Cells

• Main Authors: Gabriela Zavala (Author), María-Paz Ramos (Author), Aliosha I. Figueroa-Valdés (Author), Pablo Cisternas (Author), Ursula Wyneken (Author), Macarena Hernández (Author), Pauline Toa (Author), Brian Salmons (Author), John Dangerfield (Author), Walter H. Gunzburg (Author), Maroun Khoury (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The clinical benefit of therapies using Mesenchymal Stem Cells (MSCs) is attributable to their pleiotropic effect over cells and tissues, mainly through their secretome. This paracrine effect is mediated by secreted growth factors and extracellular vesicles (EV) including small EV (sEV). sEV are ext...