Insulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesity

• Main Authors: Anika K. Anam (Author), Katherine M. Cooke (Author), Milana Bochkur Dratver (Author), Jane V. O'Bryan (Author), Lauren E. Perley (Author), Seth M. Guller (Author), Janice J. Hwang (Author), Hugh S. Taylor (Author), Leigh Goedeke (Author), Harvey J. Kliman (Author), Daniel F. Vatner (Author), Clare A. Flannery (Author)
• Format: Book
• Published: Elsevier, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Maternal obesity increases the incidence of excess adiposity in newborns, resulting in lifelong diabetes risk. Elevated intrauterine fetal adiposity has been attributed to maternal hyperglycemia; however, this hypothesis does not account for the increased adiposity seen in newborns of mot...