Reversal of cisplatin triggered neurotoxicity by Acacia hydaspica ethyl acetate fraction via regulating brain acetylcholinesterase activity, DNA damage, and pro-inflammatory cytokines in the rodent model

• Main Authors: Tayyaba Afsar (Author), Suhail Razak (Author), Ali Almajwal (Author)
• Formato: Libro
• Publicado: BMC, 2022-07-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Abstract Background Cisplatin (CisPT) is a chemotherapeutic that outcome in adverse effects including neurotoxicity. We examined the efficacy of hydaspica ethyl acetate extract (AHE) against CisPT-prompted neurotoxicity. Methods Group I: Distilled water; Group II: CisPT (12 mg/kg b.w. i.p) on the 13...