Reversal of cisplatin triggered neurotoxicity by Acacia hydaspica ethyl acetate fraction via regulating brain acetylcholinesterase activity, DNA damage, and pro-inflammatory cytokines in the rodent model

• Những tác giả chính: Tayyaba Afsar (Tác giả), Suhail Razak (Tác giả), Ali Almajwal (Tác giả)
• Định dạng: Sách
• Được phát hành: BMC, 2022-07-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Abstract Background Cisplatin (CisPT) is a chemotherapeutic that outcome in adverse effects including neurotoxicity. We examined the efficacy of hydaspica ethyl acetate extract (AHE) against CisPT-prompted neurotoxicity. Methods Group I: Distilled water; Group II: CisPT (12 mg/kg b.w. i.p) on the 13...