Binding characterization of anthraquinone derivatives by stabilizing G-quadruplex DNA leads to an anticancerous activity
G-quadruplex is a non-canonical secondary structure identified in the telomeric region and the promoter of many oncogenes. Anthraquinone derivatives, a well-known inducer of telomere disruption in malignant cells and activate the apoptotic pathway. We used biophysical and biochemical studies to conf...
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Format: | Book |
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Elsevier,
2022-12-01T00:00:00Z.
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Internet
Connect to this object online.3rd Floor Main Library
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A1234.567 |
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