Binding characterization of anthraquinone derivatives by stabilizing G-quadruplex DNA leads to an anticancerous activity
G-quadruplex is a non-canonical secondary structure identified in the telomeric region and the promoter of many oncogenes. Anthraquinone derivatives, a well-known inducer of telomere disruption in malignant cells and activate the apoptotic pathway. We used biophysical and biochemical studies to conf...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Kitap |
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Elsevier,
2022-12-01T00:00:00Z.
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