Neuropeptide deficient mice have attenuated nociceptive, vascular, and inflammatory changes in a tibia fracture model of complex regional pain syndrome

• Main Authors: Guo Tian-Zhi (Author), Wei Tzuping (Author), Shi Xiaoyou (Author), Li Wen-Wu (Author), Hou Saiyun (Author), Wang Liping (Author), Tsujikawa Kazutake (Author), Rice Kenner C (Author), Cheng Kejun (Author), Clark David J (Author), Kingery Wade S (Author)
• Format: Book
• Published: SAGE Publishing, 2012-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Distal limb fracture in man can induce a complex regional pain syndrome (CRPS) with pain, warmth, edema, and cutaneous inflammation. In the present study substance P (SP, Tac1^−/−) and CGRP receptor (RAMP1<su...