TLR9-Dependent Activation by Inactivated Parapoxvirus Ovis in Murine Bone Marrow-Derived Dendritic Cells Is Associated with Specific Strain-Dependent Dendritic Cell Subsets

• Main Authors: Yanqin Du (Author), Hang Sun (Author), Sonakshi Bhattacharjee (Author), Alexander Birkmann (Author), Ulf Dittmer (Author), Mengji Lu (Author)
• Format: Book
• Published: Karger Publishers, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Inactivated parapoxvirus ovis (iPPVO) exerts strong immunomodulatory effects on innate immune cells, making it an attractive therapeutic candidate. However, little is known about the signaling pathways that are involved in iPPVO-induced immune responses. Methods: In this study, we syst...