TLR9-Dependent Activation by Inactivated Parapoxvirus Ovis in Murine Bone Marrow-Derived Dendritic Cells Is Associated with Specific Strain-Dependent Dendritic Cell Subsets

• Главные авторы: Yanqin Du (Автор), Hang Sun (Автор), Sonakshi Bhattacharjee (Автор), Alexander Birkmann (Автор), Ulf Dittmer (Автор), Mengji Lu (Автор)
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• Опубликовано: Karger Publishers, 2024-06-01T00:00:00Z.
• Предметы: article
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Introduction: Inactivated parapoxvirus ovis (iPPVO) exerts strong immunomodulatory effects on innate immune cells, making it an attractive therapeutic candidate. However, little is known about the signaling pathways that are involved in iPPVO-induced immune responses. Methods: In this study, we syst...