Cover Image

Simultaneous Quantification of Propylthiouracil and Its <i>N</i>-β-<span style="font-variant: small-caps">d</span> Glucuronide by HPLC-MS/MS: Application to a Metabolic Study

Propylthiouracil (PTU) is commonly prescribed for the management of hyperthyroidism and thyrotoxicosis. Although the exact mechanism of action is not fully understood, PTU is associated with hepatoxicity in pediatric population. Glucuronidation mediated by uridine 5'-diphospho-glucuronosyltrans...

Full description

Saved in:

Bibliographic Details
Main Authors:	Min Li (Author), Qingfeng He (Author), Li Yao (Author), Xiaofeng Wang (Author), Zhijia Tang (Author), Xiao Zhu (Author), Hai-Shu Lin (Author), Xiaoqiang Xiang (Author)
Format:	Book
Published:	MDPI AG, 2021-11-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Effects of Dietary Supplementation with <span style="font-variant: small-caps">dl</span>-Methionine and <span style="font-variant: small-caps">dl</span>-Methionyl-<span style="font-variant: small-caps">dl</span>-Methionine in Breeding Pigeons on the Carcass Characteristics, Meat Quality and Antioxidant Activity of Squabs
by: Shi-Guang Jiang, et al.
Published: (2019)

Novel Nanocombinations of <span style="font-variant: small-caps">l</span>-Tryptophan and <span style="font-variant: small-caps">l</span>-Cysteine: Preparation, Characterization, and Their Applications for Antimicrobial and Anticancer Activities
by: Ahmed I. Abd-Elhamid, et al.
Published: (2021)

<span style="font-variant: small-caps">l</span>-Ornithine-<span style="font-variant: small-caps">l</span>-Aspartate (LOLA) Normalizes Metabolic Parameters in Models of Steatosis, Insulin Resistance and Metabolic Syndrome
by: Ali Canbay, et al.
Published: (2024)

Polymer Conjugates of Antimicrobial Peptides (AMPs) with <span style="font-variant: small-caps">d</span>-Amino Acids (<span style="font-variant: small-caps">d</span>-aa): State of the Art and Future Opportunities
by: Ottavia Bellotto, et al.
Published: (2022)

Physicochemical, Pharmacokinetic, and Toxicity Evaluation of Methoxy Poly(ethylene glycol)-<i>b</i>-Poly(<span style="font-variant: small-caps">d</span>,<span style="font-variant: small-caps">l</span>-Lactide) Polymeric Micelles Encapsulating Alpinumisoflavone Extracted from Unripe <i>Cudrania tricuspidata</i> Fruit
by: Min Jeong Jo, et al.
Published: (2019)

Antioxidant Effects of <i>Apocynum venetum</i> Tea Extracts on <span style="font-variant: small-caps">d</span>-Galactose-Induced Aging Model in Mice
by: Chong Li, et al.
Published: (2019)

Effects of Decomplexation Rates on Ternary Gene Complex Transfection with <i>α</i>-Poly(<span style="font-variant: small-caps">l</span>-Lysine) or <i>ε</i>-Poly(<span style="font-variant: small-caps">l</span>-Lysine) as a Decomplexation Controller in An Easy-To-Transfect Cell or A Hard-To-Transfect Cell
by: Kyoungnam Kim, et al.
Published: (2020)

<span style="font-variant: small-caps">d</span>-Cysteine-Induced Rapid Root Abscission in the Water Fern <i>Azolla Pinnata</i>: Implications for the Linkage between <span style="font-variant: small-caps">d</span>-Amino Acid and Reactive Sulfur Species (RSS) in Plant Environmental Responses
by: Hideo Yamasaki, et al.
Published: (2019)

Effect of Oxaliplatin-Loaded Poly (<span style="font-variant: small-caps">d</span>,<span style="font-variant: small-caps">l</span>-Lactide-<i>co</i>-Glycolic Acid) (PLGA) Nanoparticles Combined with Retinoic Acid and Cholesterol on Apoptosis, Drug Resistance, and Metastasis Factors of Colorectal Cancer
by: Ana Luiza C. de S. L. Oliveira, et al.
Published: (2020)

Photothermally Controlled Drug Release of Poly(<span style="font-variant: small-caps">d</span>,<span style="font-variant: small-caps">l</span>-lactide) Nanofibers Loaded with Indocyanine Green and Curcumin for Efficient Antimicrobial Photodynamic Therapy
by: Bernd Gutberlet, et al.
Published: (2023)

Effect of Solvents, Stabilizers and the Concentration of Stabilizers on the Physical Properties of Poly(<span style="font-variant: small-caps">d</span>,<span style="font-variant: small-caps">l</span>-lactide-<i>co</i>-glycolide) Nanoparticles: Encapsulation, In Vitro Release of Indomethacin and Cytotoxicity against HepG2-Cell
by: Musaed Alkholief, et al.
Published: (2022)

<span style="font-variant: small-caps">l</span>-Asparaginase Type II from <i>Fusarium proliferatum</i>: Heterologous Expression and In Silico Analysis
by: Samuel Leite Cardoso, et al.
Published: (2023)

<span style="font-variant: small-caps">l</span>-Arginine and Beetroot Extract Supplementation in the Prevention of Sarcopenia
by: Alfredo Córdova-Martínez, et al.
Published: (2022)

Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly(<span style="font-variant: small-caps">l</span>-Glutamic Acid)-Poly(<span style="font-variant: small-caps">l</span>-Phenylalanine) Triblock Polymer for Sustained Drug Delivery
by: Xingzheng Liu, et al.
Published: (2018)

Polyamine Induction in Postharvest Banana Fruits in Response to NO Donor SNP Occurs via <span style="font-variant: small-caps">l</span>-Arginine Mediated Pathway and Not via Competitive Diversion of S-Adenosyl-<span style="font-variant: small-caps">l</span>-Methionine
by: Veeresh Lokesh, et al.
Published: (2019)

Correction of Experimental Retinal Ischemia by <span style="font-variant: small-caps">l</span>-Isomer of Ethylmethylhydroxypyridine Malate
by: Anna Peresypkina, et al.
Published: (2019)

<i>N</i>-Nonyloxypentyl-<span style="font-variant: small-caps">l</span>-Deoxynojirimycin Inhibits Growth, Biofilm Formation and Virulence Factors Expression of <i>Staphylococcus aureus</i>
by: Eliana De Gregorio, et al.
Published: (2020)

<span style="font-variant: small-caps">l</span>-Cysteine and <span style="font-variant: small-caps">l</span>-Serine Modified Dendrimer with Multiple Reduced Thiols as a Kidney-Targeting Reactive Oxygen Species Scavenger to Prevent Renal Ischemia/Reperfusion Injury
by: Satoru Matsuura, et al.
Published: (2018)

Synthesis, Antimicrobial and Mutagenic Activity of a New Class of <span style="font-variant: small-caps">d</span>-Xylopyranosides
by: Karol Sikora, et al.
Published: (2023)

Colorants and Antioxidants Deriving from Methylglyoxal and Heterocyclic <span style="font-variant: small-caps">Maillard</span> Reaction Intermediates
by: Leon Valentin Bork, et al.
Published: (2023)

Sulfuric Odor Precursor <i>S</i>-Allyl-<span style="font-variant: small-caps">l</span>-Cysteine Sulfoxide in Garlic Induces Detoxifying Enzymes and Prevents Hepatic Injury
by: Yusuke Yamaguchi, et al.
Published: (2019)

Dimethyl Fumarate (DMF) Alleviated Post-Operative (PO) Pain through the <i>N</i>-Methyl-<span style="font-variant: small-caps">d</span>-Aspartate (NMDA) Receptors
by: Giovanna Casili, et al.
Published: (2022)

Isolation, Characterization and Chemical Synthesis of Large Spectrum Antimicrobial Cyclic Dipeptide (<span style="font-variant: small-caps">l</span>-leu-<span style="font-variant: small-caps">l</span>-pro) from <i>Streptomyces misionensis</i> V16R3Y1 Bacteria Extracts. A Novel <sup>1</sup>H NMR Metabolomic Approach
by: Ilhem Saadouli, et al.
Published: (2020)

Uniting Electroceutical and Cosmeceutical Interventions in Combating Coronavirus Using Ԑ-Poly-<span style="font-variant: small-caps">l</span>-Lysine
by: Rania M. Hathout, et al.
Published: (2020)

Multi-Modulation of Doxorubicin Resistance in Breast Cancer Cells by Poly(<span style="font-variant: small-caps">l</span>-histidine)-Based Multifunctional Micelles
by: Li Jia, et al.
Published: (2019)

Flavonoid-Rich Extract of <i>Paeonia lactiflora</i> Petals Alleviate <span style="font-variant: small-caps">d</span>-Galactose-Induced Oxidative Stress and Restore Gut Microbiota in ICR Mice
by: Lei Liu, et al.
Published: (2021)

Involvement of <span style="font-variant: small-caps">l</span>-Cysteine Desulfhydrase and Hydrogen Sulfide in Glutathione-Induced Tolerance to Salinity by Accelerating Ascorbate-Glutathione Cycle and Glyoxalase System in <i>Capsicum</i>
by: Cengiz Kaya, et al.
Published: (2020)

<span style="font-variant: small-caps">d</span>-Galactose Decreases Anion Exchange Capability through Band 3 Protein in Human Erythrocytes
by: Alessia Remigante, et al.
Published: (2020)

OCTN2-Mediated Acetyl-<span style="font-variant: small-caps">l</span>-Carnitine Transport in Human Pulmonary Epithelial Cells In Vitro
by: Johanna J. Salomon, et al.
Published: (2019)

<span style="font-variant: small-caps">l</span>-Arginine Induces White Adipose Tissue Browning-A New Pharmaceutical Alternative to Cold
by: Andjelika Kalezic, et al.
Published: (2022)

Poly(<span style="font-variant: small-caps">l</span>-Ornithine)-Based Polymeric Micelles as pH-Responsive Macromolecular Anticancer Agents
by: Miao Pan, et al.
Published: (2023)

Systematic Review of <span style="font-variant: small-caps">l</span>-Arginine for the Treatment of Hypoactive Sexual Desire Disorder and Related Conditions in Women
by: Nicole E. Cieri-Hutcherson, et al.
Published: (2021)

In Vitro and In Vivo Antioxidant Properties of <i>Taraxacum officinale</i> in <i>N</i>ω-Nitro-<span style="font-variant: small-caps">l</span>-Arginine Methyl Ester (L-NAME)-Induced Hypertensive Rats
by: Olukayode O. Aremu, et al.
Published: (2019)

<i>p</i>-Hydroxybenzoic Acid β-<span style="font-variant: small-caps">d</span>-Glucosyl Ester and Cimidahurinine with Antimelanogenesis and Antioxidant Effects from <i>Pyracantha angustifolia</i> via Bioactivity-Guided Fractionation
by: Sun-Yup Shim, et al.
Published: (2020)

Antibacterial Activity of Linezolid against Gram-Negative Bacteria: Utilization of ε-Poly-<span style="font-variant: small-caps">l</span>-Lysine Capped Silica Xerogel as an Activating Carrier
by: Gulcihan Guzel Kaya, et al.
Published: (2020)

An Antibacterial Peptide with High Resistance to Trypsin Obtained by Substituting <span style="font-variant: small-caps">d</span>-Amino Acids for Trypsin Cleavage Sites
by: Xiaoou Zhao, et al.
Published: (2021)

Fabrication and Biological Activities of Plasmid DNA Gene Carrier Nanoparticles Based on Biodegradable <span style="font-variant: small-caps">l</span>-Tyrosine Polyurethane
by: Soo-Yong Park, et al.
Published: (2021)

Evaluation of 3-Borono-<span style="font-variant: small-caps">l</span>-Phenylalanine as a Water-Soluble Boron Neutron Capture Therapy Agent
by: Naoya Kondo, et al.
Published: (2022)

Filamentous Fungi Producing <span style="font-variant: small-caps">l</span>-Asparaginase with Low Glutaminase Activity Isolated from Brazilian Savanna Soil
by: Marcela Freitas, et al.
Published: (2021)

Polyurea Dendrimer Folate-Targeted Nanodelivery of <span style="font-variant: small-caps">l</span>-Buthionine Sulfoximine as a Tool to Tackle Ovarian Cancer Chemoresistance
by: Adriana Cruz, et al.
Published: (2020)