The establishment and application of preimplantation genetic haplotyping in embryo diagnosis for reciprocal and Robertsonian translocation carriers

• Main Authors: Shuo Zhang (Author), Caixia Lei (Author), Junping Wu (Author), Jing Zhou (Author), Haiyan Sun (Author), Jing Fu (Author), Yijuan Sun (Author), Xiaoxi Sun (Author), Daru Lu (Author), Yueping Zhang (Author)
• Format: Book
• Published: BMC, 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Preimplantation genetic diagnosis (PGD) is now widely used to select embryos free of chromosomal copy number variations (CNV) from chromosome balanced translocation carriers. However, it remains a difficulty to distinguish in embryos between balanced and structurally normal chrom...