The Fibrin Cleavage Product Bβ15-42 Channels Endothelial and Tubular Regeneration in the Post-acute Course During Murine Renal Ischemia Reperfusion Injury

• Main Authors: Dania Fischer (Author), Christopher Seifen (Author), Patrick Baer (Author), Michaela Jung (Author), Christina Mertens (Author), Bertram Scheller (Author), Kai Zacharowski (Author), Rainer Hofmann (Author), Thorsten J. Maier (Author), Anja Urbschat (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Early and adequate restoration of endothelial and tubular renal function is a substantial step during regeneration after ischemia reperfusion (IR) injury, occurring, e.g., in kidney transplantation, renal surgery, and sepsis. While tubular epithelial cell injury has long been of central importance,...