Preparation and in vivo evaluation of an intravenous emulsion loaded with an aprepitant-phospholipid complex

• Main Authors: Yan Li (Author), Hong Yin (Author), Chensi Wu (Author), Jia He (Author), Chunyan Wang (Author), Bo Ren (Author), Heping Wang (Author), Dandan Geng (Author), Yirong Zhang (Author), Ligang Zhao (Author)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

AbstractIn present, there was no detailed report on the formulation optimization and quality evaluation of aprepitant (APT) injectable lipid emulsion (APT-IE). The aim of the present investigation was to prepare and evaluate its properties of APT-IE loaded with an APT phospholipid complex (APT-PC) i...