One-Pot Synthesis and Molecular Modeling Studies of New Bioactive Spiro-Oxindoles Based on Uracil Derivatives as SARS-CoV-2 Inhibitors Targeting RNA Polymerase and Spike Glycoprotein

• المؤلفون الرئيسيون: Samar A. El-Kalyoubi (مؤلف), Ahmed Ragab (مؤلف), Ola A. Abu Ali (مؤلف), Yousry A. Ammar (مؤلف), Mohamed G. Seadawy (مؤلف), Aya Ahmed (مؤلف), Eman A. Fayed (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2022-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The first outbreak in Wuhan, China, in December 2019 was reported about severe acute coronaviral syndrome 2 (SARS-CoV-2). The global coronavirus disease 2019 (COVID-19) pandemic in 2020 resulted in an extremely high potential for dissemination. No drugs are validated in large-scale studies for signi...