Radioimmunotheranostic Pair Based on the Anti-HER2 Monoclonal Antibody: Influence of Chelating Agents and Radionuclides on Biological Properties

• Main Authors: Ana Cláudia Camargo Miranda (Author), Sofia Nascimento dos Santos (Author), Leonardo Lima Fuscaldi (Author), Luiza Mascarenhas Balieiro (Author), Maria Helena Bellini (Author), Maria Inês Calil Cury Guimarães (Author), Elaine Bortoleti de Araújo (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The oncogene HER2 is an important molecular target in oncology because it is associated with aggressive disease and the worst prognosis. The development of non-invasive imaging techniques and target therapies using monoclonal antibodies is a rapidly developing field. Thus, this work proposes the stu...