Unravelling the genetic causes of mosaic islet morphology in congenital hyperinsulinism

• Hlavní autoři: Jayne AL Houghton (Autor), Indraneel Banerjee (Autor), Guftar Shaikh (Autor), Shamila Jabbar (Autor), Thomas W Laver (Autor), Edmund Cheesman (Autor), Amish Chinnoy (Autor), Daphne Yau (Autor), Maria Salomon‐Estebanez (Autor), Mark J Dunne (Autor), Sarah E Flanagan (Autor)
• Médium: Kniha
• Vydáno: Wiley, 2020-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Abstract Congenital hyperinsulinism (CHI) causes dysregulated insulin secretion which can lead to life‐threatening hypoglycaemia if not effectively managed. CHI can be sub‐classified into three distinct groups: diffuse, focal and mosaic pancreatic disease. Whilst the underlying causes of diffuse and...