Single-cell transcriptomic analysis reveals a decrease in the frequency of macrophage-RGS1high subsets in patients with osteoarticular tuberculosis

• Main Authors: Ying Jiang (Author), Xinqiang Zhang (Author), Bo Wang (Author), Liping Tang (Author), Xin Liu (Author), Xiudong Ding (Author), Yueming Dong (Author), Hong Lei (Author), Di Wang (Author), Huicheng Feng (Author)
• Format: Book
• Published: BMC, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cell subsets differentially modulate host immune responses to Mycobacterium tuberculosis (MTB) infection. However, the nature and functions of these subsets against osteoarticular tuberculosis (OTB) are unclear. Here, we aimed to understand the phenotypes and functions of immune...