Clinical Utility and Implementation of Pharmacogenomics for the Personalisation of Antipsychotic Treatments

• Main Authors: Marta Hernandez (Author), Natalia Cullell (Author), Marc Cendros (Author), Alexandre Serra-Llovich (Author), Maria J. Arranz (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Decades of pharmacogenetic research have revealed genetic biomarkers of clinical response to antipsychotics. Genetic variants in antipsychotic targets, dopamine and serotonin receptors in particular, and in metabolic enzymes have been associated with the efficacy and toxicity of antipsychotic treatm...