L type Ca²⁺channel blockers prevent oxaliplatin-induced cold hyperalgesia and TRPM8 overexpression in rats

• Main Authors: Kawashiri Takehiro (Author), Egashira Nobuaki (Author), Kurobe Kentaro (Author), Tsutsumi Kuniaki (Author), Yamashita Yuji (Author), Ushio Soichiro (Author), Yano Takahisa (Author), Oishi Ryozo (Author)
• Format: Book
• Published: SAGE Publishing, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Oxaliplatin is an important drug used in the treatment of colorectal cancer. However, it frequently causes severe acute and chronic peripheral neuropathies. We recently reported that repeated administration of oxaliplatin induced col...