Orally active antischistosomal early leads identified from the open access malaria box.

• Main Authors: Katrin Ingram-Sieber (Author), Noemi Cowan (Author), Gordana Panic (Author), Mireille Vargas (Author), Nuha R Mansour (Author), Quentin D Bickle (Author), Timothy N C Wells (Author), Thomas Spangenberg (Author), Jennifer Keiser (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Worldwide hundreds of millions of schistosomiasis patients rely on treatment with a single drug, praziquantel. Therapeutic limitations and the threat of praziquantel resistance underline the need to discover and develop next generation drugs.We studied the antischistosomal properties of the Medicine...