Expanding the recognition interface of the thrombin-binding aptamer HD1 through modification of residues T3 and T12
Post-SELEX modification of DNA aptamers is an established strategy to improve their affinity or inhibitory characteristics. In this study, we examined the possibility of increasing the recognition interface between the thrombin-binding aptamer HD1 (TBA) and thrombin by adding a chemically modified s...
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Main Authors: | , , , , |
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Format: | Book |
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Elsevier,
2021-03-01T00:00:00Z.
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Internet
Connect to this object online.3rd Floor Main Library
Call Number: |
A1234.567 |
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Copy 1 | Available |