IL-23 inhibitor enhances the effects of PTEN DNA-loaded lipid nanoparticles for metastatic CRPC therapy

• Main Authors: Xinlu Chen (Author), Luyao Gong (Author), Yuanyuan Wang (Author), Chen Ye (Author), Huanhuan Guo (Author), Shen Gao (Author), Jiyuan Chen (Author), Zhuo Wang (Author), Yuan Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Metastatic castration-resistant prostate cancer (mCRPC) patients face challenges due to limited treatment options. About 50% of patients with mCRPC have a functional loss of phosphatase and tensin homology deleted on chromosome 10 (PTEN), leading to tumor progression, metastasis, and i...