Caffeine reduces oxidative stress to protect against hyperoxia-induced lung injury via the adenosine A2A receptor/cAMP/PKA/Src/ERK1/2/p38MAPK pathway

• المؤلفون الرئيسيون: Xijuan Wang (مؤلف), Shuai Lv (مؤلف), Jianwei Sun (مؤلف), Meihui Zhang (مؤلف), Lei Zhang (مؤلف), Yan Sun (مؤلف), Ziyan Zhao (مؤلف), Dandan Wang (مؤلف), Xinjing Zhao (مؤلف), Jiajie Zhang (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Objectives: Caffeine has been shown to reduce the incidence of bronchopulmonary dysplasia (BPD). To investigate the protective mechanism of caffeine in a hyperoxia-based cell model of BPD in vitro.Methods: Type II alveolar epithelial cells (AECs II) were isolated and randomly divided into 6 groups:...