Transient Receptor Potential Melastatin 7 (TRPM7) Contributes to H2O2-Induced Cardiac Fibrosis via Mediating Ca2+ Influx and Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Activation in Cardiac Fibroblasts

• Egile Nagusiak: Jin-Lei Guo (Egilea), Yang Yu (Egilea), Yan-Yan Jia (Egilea), Yun-Zi Ma (Egilea), Bo-Yu Zhang (Egilea), Pei-Qing Liu (Egilea), Shao-Rui Chen (Egilea), Jian-Min Jiang (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2014-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract.: Transient receptor potential melastatin 7 (TRPM7), a Ca2+-nonselective cation channel, plays a key role in the pathophysiological response of multiple cell types. However, the role of TRPM7 channels in hydrogen peroxide (H2O2)-induced cardiac fibrosis remains unclear. This study aimed to...