Transient Receptor Potential Melastatin 7 (TRPM7) Contributes to H2O2-Induced Cardiac Fibrosis via Mediating Ca2+ Influx and Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Activation in Cardiac Fibroblasts

Abstract.: Transient receptor potential melastatin 7 (TRPM7), a Ca2+-nonselective cation channel, plays a key role in the pathophysiological response of multiple cell types. However, the role of TRPM7 channels in hydrogen peroxide (H2O2)-induced cardiac fibrosis remains unclear. This study aimed to...

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Main Authors: Jin-Lei Guo (Author), Yang Yu (Author), Yan-Yan Jia (Author), Yun-Zi Ma (Author), Bo-Yu Zhang (Author), Pei-Qing Liu (Author), Shao-Rui Chen (Author), Jian-Min Jiang (Author)
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出版: Elsevier, 2014-01-01T00:00:00Z.
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索引号: A1234.567
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