Druggable cavities and allosteric modulators of the cell division cycle 7 (CDC7) kinase

AbstractCell division cycle 7 kinase (CDC7) has been found overexpressed in many cancer cell lines being also one of the kinases involved in the nuclear protein TDP-43 phosphorylation in vivo. Thus, inhibitors of CDC7 are emerging drug candidates for the treatment of oncological and neurodegenerativ...

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Main Authors: Elisa Rojas-Prats (Author), Loreto Martinez-Gonzalez (Author), Carmen Gil (Author), David Ramírez (Author), Ana Martinez (Author)
Format: Book
Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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