Microbiota Imbalance Contributes to COPD Deterioration by Enhancing IL-17a Production via miR-122 and miR-30a

• Egile Nagusiak: Ke Zhu (Egilea), Sijing Zhou (Egilea), Aiqun Xu (Egilea), Li Sun (Egilea), Min Li (Egilea), Huihui Jiang (Egilea), Binbin Zhang (Egilea), Daxiong Zeng (Egilea), Guanghe Fei (Egilea), Ran Wang (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2020-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The changes of microbiota in lungs could change interleukin-17a (IL-17a) expression by altering microRNAs (miRNAs) profile, thus contributing to the pathogenesis of chronic obstructive pulmonary disease (COPD). In this study, we aimed to study molecular mechanisms' underlying effect of microbio...