Synthesis, Biological Activity, and Molecular Modelling Studies of Naphthoquinone Derivatives as Promising Anticancer Candidates Targeting COX-2

• Main Authors: Povilas Kavaliauskas (Author), Felipe Stambuk Opazo (Author), Waldo Acevedo (Author), Ruta Petraitiene (Author), Birutė Grybaitė (Author), Kazimieras Anusevičius (Author), Vytautas Mickevičius (Author), Sergey Belyakov (Author), Vidmantas Petraitis (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-associated mortalities worldwide. Therefore, it is crucial to develop a novel therapeutic option targeting localized and metastatic NSCLC. In this paper, we describe the synthesis and biological activity characterization of naphtho...