Conquering the beyond Rule of Five Space with an Optimized High-Throughput Caco-2 Assay to Close Gaps in Absorption Prediction

Current drug development tends towards complex chemical molecules, referred to as "beyond rule of five" (bRo5) compounds, which often exhibit challenging physicochemical properties. Measuring Caco-2 permeability of those compounds is difficult due to technical limitations, including poor r...

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Main Authors: Patricia Muschong (Author), Khader Awwad (Author), Edward Price (Author), Mario Mezler (Author), Manuel Weinheimer (Author)
Format: Book
Published: MDPI AG, 2024-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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