Development and Evaluation of Solid Lipid Nanoparticles for the Clearance of Aβ in Alzheimer's Disease

• Main Authors: Meghana Goravinahalli Shivananjegowda (Author), Umme Hani (Author), Riyaz Ali M. Osmani (Author), Ali H. Alamri (Author), Mohammed Ghazwani (Author), Yahya Alhamhoom (Author), Mohamed Rahamathulla (Author), Sathishbabu Paranthaman (Author), Devegowda Vishakante Gowda (Author), Ayesha Siddiqua (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aggregation of Amyloid-β (Aβ) leads to the formation and deposition of neurofibrillary tangles and plaques which is the main pathological hallmark of Alzheimer's disease (AD). The bioavailability of the drugs and their capability to cross the BBB plays a crucial role in the therapeutics of AD....