G Protein-Coupled Receptor Kinase 2 (GRK2) as a Potential Therapeutic Target in Cardiovascular and Metabolic Diseases

• Hoofdauteurs: Cristina Murga (Auteur), Alba C. Arcones (Auteur), Marta Cruces-Sande (Auteur), Ana M. Briones (Auteur), Mercedes Salaices (Auteur), Federico Mayor Jr (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2019-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

G protein-coupled receptor kinase 2 (GRK2) is a central signaling node involved in the modulation of many G protein-coupled receptors (GPCRs) and also displaying regulatory functions in other cell signaling routes. GRK2 levels and activity have been reported to be enhanced in patients or in preclini...