Integrating metabolomics, bionics, and culturomics to study probiotics-driven drug metabolism

• Główni autorzy: Bohai Li (Autor), Lai-Yu Kwok (Autor), Dandan Wang (Autor), Lu Li (Autor), Shuai Guo (Autor), Yongfu Chen (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Many drugs have been shown to be metabolized by the human gut microbiome, but probiotic-driven drug-metabolizing capacity is rarely explored. Here, we developed an integrated metabolomics, culturomics, and bionics framework for systematically studying probiotics-driven drug metabolism. We discovered...