DNA methylation of HOX genes and its clinical implications in cancer

• Main Authors: Xin Hu (Author), Yong Wang (Author), Xiaoyu Zhang (Author), Chensheng Li (Author), Xikun Zhang (Author), Dongxia Yang (Author), Yuanyuan Liu (Author), Lianlian Li (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Homeobox (HOX) genes encode highly conserved transcription factors that play vital roles in embryonic development. DNA methylation is a pivotal regulatory epigenetic signaling mark responsible for regulating gene expression. Abnormal DNA methylation is largely associated with the aberrant expression...