Human targeted phenobarbital presents a poor substrate of gut microbiome deciphering new drug targets beyond pharmacokinetic curbs

Abstract Background The gut microbiome, a new organ of the body, can potentially alter the pharmacokinetics of orally administered drugs through microbial enzymes. However, absorption of orally administered non-antibiotic drugs by the gut microbiome, during drug-microbiome interaction, is barely add...

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Hlavní autoři: Imran Mukhtar (Autor), Haseeb Anwar (Autor), Arslan Iftikhar (Autor), Heba E. Hashem (Autor), Qasim Ali (Autor), Farhan Siddique (Autor)
Médium: Kniha
Vydáno: BMC, 2022-11-01T00:00:00Z.
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