In silico trial for the assessment of givinostat dose adjustment rules based on the management of key hematological parameters in polycythemia vera patients

In silico trial for the assessment of givinostat dose adjustment rules based on the management of key hematological parameters in polycythemia vera patients

Abstract Polycythemia vera (PV) is a chronic myeloproliferative neoplasm characterized by excessive levels of platelets (PLT), white blood cells (WBC), and hematocrit (HCT). Givinostat (ITF2357) is a potent histone‐deacetylase inhibitor that showed a good safety/efficacy profile in PV patients durin...

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Main Authors: Elena M. Tosca (Author), Alessandro De Carlo (Author), Roberta Bartolucci (Author), Francesco Fiorentini (Author), Silvia Di Tollo (Author), Maurizio Caserini (Author), Maurizio Rocchetti (Author), Paolo Bettica (Author), Paolo Magni (Author)
Format: Book
Published: Wiley, 2024-03-01T00:00:00Z.
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