Ivacaftor pharmacokinetics and lymphatic transport after enteral administration in rats
Background: Ivacaftor is a modern drug used in the treatment of cystic fibrosis. It is highly lipophilic and exhibits a strong positive food effect. These characteristics can be potentially connected to a pronounced lymphatic transport after oral administration.Methods: A series of studies was condu...
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Frontiers Media S.A.,
2024-02-01T00:00:00Z.
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