Anti-rotavirus antibody measurement in a rotavirus vaccine trial: Choice of vaccine antigen in immunoassays does matter

• Автори: Xiaoqian Wang (Автор), Daniel E. Velasquez Portocarrero (Автор), Margaret M. Cortese (Автор), Umesh Parashar (Автор), Khalequ Zaman (Автор), Baoming Jiang (Автор)
• Формат: Книга
• Опубліковано: Taylor & Francis Group, 2023-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

In a clinical trial of Bangladeshi infants who received three doses of RotaTeq (ages 6, 10, and 14 weeks), we did a head-to-head assessment of two vaccine virus strains to measure rotavirus IgA in sera. Serum samples collected at pre-dose 1 (age 6 weeks) and post-dose 3 (age 22 weeks) were tested fo...