Lysyl oxidase expression is associated with inferior outcome and Extramedullary disease of acute myeloid leukemia

• Main Authors: Desiree Kunadt (Author), Michael Kramer (Author), Claudia Dill (Author), Heidi Altmann (Author), Lisa Wagenführ (Author), Brigitte Mohr (Author), Christian Thiede (Author), Christoph Röllig (Author), Johannes Schetelig (Author), Martin Bornhäuser (Author), Markus Schaich (Author), Friedrich Stölzel (Author)
• Format: Book
• Published: BMC, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Lysyl oxidase (LOX) has been described as necessary for premetastatic niche formation in epithelium-derived malignancies and its expression level therefore correlates with risk of metastatic disease and overall survival. However, its role in acute myeloid leukemia (AML) has not b...