Formulation and In-Vitro Characterization of Chitosan-Nanoparticles Loaded with the Iron Chelator Deferoxamine Mesylate (DFO)

Formulation and In-Vitro Characterization of Chitosan-Nanoparticles Loaded with the Iron Chelator Deferoxamine Mesylate (DFO)

The objective of this study was to develop chitosan (CS) nanoparticles (NPs) loaded with deferoxamine mesylate (DFO) for slow release of this iron-chelating drug. Drug nanoencapsulation was performed via ionic gelation of chitosan using sodium tripolyphosphate (TPP) as cross-linker. Nanoparticles wi...

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Main Authors: Maria Lazaridou (Author), Evi Christodoulou (Author), Maria Nerantzaki (Author), Margaritis Kostoglou (Author), Dimitra A. Lambropoulou (Author), Angeliki Katsarou (Author), Kostas Pantopoulos (Author), Dimitrios N. Bikiaris (Author)
Format: Book
Published: MDPI AG, 2020-03-01T00:00:00Z.
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