Formulation and In-Vitro Characterization of Chitosan-Nanoparticles Loaded with the Iron Chelator Deferoxamine Mesylate (DFO)

• প্রধান লেখক: Maria Lazaridou (লেখক), Evi Christodoulou (লেখক), Maria Nerantzaki (লেখক), Margaritis Kostoglou (লেখক), Dimitra A. Lambropoulou (লেখক), Angeliki Katsarou (লেখক), Kostas Pantopoulos (লেখক), Dimitrios N. Bikiaris (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2020-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The objective of this study was to develop chitosan (CS) nanoparticles (NPs) loaded with deferoxamine mesylate (DFO) for slow release of this iron-chelating drug. Drug nanoencapsulation was performed via ionic gelation of chitosan using sodium tripolyphosphate (TPP) as cross-linker. Nanoparticles wi...