Formulation and In-Vitro Characterization of Chitosan-Nanoparticles Loaded with the Iron Chelator Deferoxamine Mesylate (DFO)

• Asıl Yazarlar: Maria Lazaridou (Yazar), Evi Christodoulou (Yazar), Maria Nerantzaki (Yazar), Margaritis Kostoglou (Yazar), Dimitra A. Lambropoulou (Yazar), Angeliki Katsarou (Yazar), Kostas Pantopoulos (Yazar), Dimitrios N. Bikiaris (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2020-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The objective of this study was to develop chitosan (CS) nanoparticles (NPs) loaded with deferoxamine mesylate (DFO) for slow release of this iron-chelating drug. Drug nanoencapsulation was performed via ionic gelation of chitosan using sodium tripolyphosphate (TPP) as cross-linker. Nanoparticles wi...