Compartmental and COMSOL Multiphysics 3D Modeling of Drug Diffusion to the Vitreous Following the Administration of a Sustained-Release Drug Delivery System

• Autors principals: Emily Dosmar (Autor), Gabrielle Vuotto (Autor), Xingqi Su (Autor), Emily Roberts (Autor), Abigail Lannoy (Autor), Garet J. Bailey (Autor), William F. Mieler (Autor), Jennifer J. Kang-Mieler (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2021-11-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The purpose of this study was to examine antibiotic drug transport from a hydrogel drug delivery system (DDS) using a computational model and a 3D model of the eye. Hydrogel DDSs loaded with vancomycin (VAN) were synthesized and release behavior was characterized in vitro. Four different compartment...