Genome-scale analysis of the genes that contribute to Burkholderia pseudomallei biofilm formation identifies a crucial exopolysaccharide biosynthesis gene cluster.

• Main Authors: Grace I Borlee (Author), Brooke A Plumley (Author), Kevin H Martin (Author), Nawarat Somprasong (Author), Mihnea R Mangalea (Author), M Nurul Islam (Author), Mary N Burtnick (Author), Paul J Brett (Author), Ivo Steinmetz (Author), David P AuCoin (Author), John T Belisle (Author), Dean C Crick (Author), Herbert P Schweizer (Author), Bradley R Borlee (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Burkholderia pseudomallei, the causative agent of melioidosis, is an important public health threat due to limited therapeutic options for treatment. Efforts to improve therapeutics for B. pseudomallei infections are dependent on the need to understand the role of B. pseudomallei biofilm formation a...