Could prophylactic antivirals reduce dengue incidence in a high-prevalence endemic area?

• Main Authors: Yalda Jafari (Author), Oliver J Brady (Author), Joseph R Biggs (Author), Le Thuy Lien (Author), Huynh Kim Mai (Author), Hien Anh Thi Nguyen (Author), Marnix Van Loock (Author), Guillermo Herrera-Taracena (Author), Joris Menten (Author), Chihiro Iwasaki (Author), Mizuki Takegata (Author), Noriko Kitamura (Author), Hung Do Thai (Author), Bui Xuan Minh (Author), Kouichi Morita (Author), Dang Duc Anh (Author), Sam Clifford (Author), Kiesha Prem (Author), Julius Hafalla (Author), W John Edmunds (Author), Lay Myint Yoshida (Author), Martin L Hibberd (Author), Stéphane Hué (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Prophylactic drugs against dengue are currently under development. In this study, we explored how such prophylactic approaches might affect dengue cases in four communes of Nha Trang City, Vietnam. A community level dengue transmission survey indicated high levels of previous exposure to dengue (89....