The role of SIGMAR1 gene mutation and mitochondrial dysfunction in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) patients exhibit diverse pathologies such as endoplasmic reticulum (ER) stress and mitochondrial dysfunction in motor neurons. Five to ten percent of patients have familial ALS, a form of the disease caused by mutations in ALS-related genes, while sporadic forms o...

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Bibliographic Details
Main Authors: Kohji Fukunaga (Author), Yasuharu Shinoda (Author), Hideaki Tagashira (Author)
Format: Book
Published: Elsevier, 2015-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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