Synthesis of an Al18F radiofluorinated GLU-UREA-LYS(AHX)-HBED-CC PSMA ligand in an automated synthesis platform

• Main Authors: Javier Giglio (Author), Maia Zeni (Author), Eduardo Savio (Author), Henry Engler (Author)
• Format: Knjiga
• Izdano: SpringerOpen, 2018-02-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Abstract Background Overexpression of prostatic membrane antigen (PSMA) is associated with the progression and prognosis of prostate cancer. There are numerous studies using this peptide with the 68Ga radionuclide. Previous methods to synthetize 18F-labeled PSMA ligands with complexes [18F]AlF2+ hav...