Targeting Some Key Metalloproteinases by Nano-Naringenin and <i>Amphora coffeaeformis</i> as a Novel Strategy for Treatment of Osteoarthritis in Rats

• Main Authors: Nema S. Shaban (Author), Abeer M. Radi (Author), Mohamed A. Abdelgawad (Author), Mohammed M. Ghoneim (Author), Rasha Hamed Al-Serwi (Author), Randa M. Hassan (Author), Eman T. Mohammed (Author), Rania A. Radi (Author), Fatma M. Halfaya (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoarthritis (OA) represents the highest degenerative disorder. Because cartilage erosion is a common pathological alteration in OA, targeting some key metalloproteinases such as MMP-3, ADAMTS-5 besides their inhibitor TIMP-3 by natural products, could be an effective strategy to protect against o...