Mutation Test in Korean Patients with Colorectal Carcinomas: A Methodological Comparison between Sanger Sequencing and a Real-Time PCR-Based Assay

• Egile Nagusiak: Sung Hak Lee (Egilea), Arthur Minwoo Chung (Egilea), Ahwon Lee (Egilea), Woo Jin Oh (Egilea), Yeong Jin Choi (Egilea), Youn-Soo Lee (Egilea), Eun Sun Jung (Egilea)
• Formatua: Liburua
• Argitaratua: Korean Society of Pathologists & the Korean Society for Cytopathology, 2017-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background Mutations in the KRAS gene have been identified in approximately 50% of colorectal cancers (CRCs). KRAS mutations are well established biomarkers in anti-epidermal growth factor receptor therapy. Therefore, assessment of KRAS mutations is needed in CRC patients to ensure appropriate treat...