Mutation Test in Korean Patients with Colorectal Carcinomas: A Methodological Comparison between Sanger Sequencing and a Real-Time PCR-Based Assay

• Päätekijät: Sung Hak Lee (Tekijä), Arthur Minwoo Chung (Tekijä), Ahwon Lee (Tekijä), Woo Jin Oh (Tekijä), Yeong Jin Choi (Tekijä), Youn-Soo Lee (Tekijä), Eun Sun Jung (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Korean Society of Pathologists & the Korean Society for Cytopathology, 2017-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Background Mutations in the KRAS gene have been identified in approximately 50% of colorectal cancers (CRCs). KRAS mutations are well established biomarkers in anti-epidermal growth factor receptor therapy. Therefore, assessment of KRAS mutations is needed in CRC patients to ensure appropriate treat...