The effect of OCT-2 inhibitor Daclatasvir on Metformin pharmacokinetics and pharmacodynamics at two dose levels: A Bayesian approach using Markov-Chain Monte Carlo simulations
Renal Organic Cation Transporter 2 (OCT2) plays a major role in metformin elimination. Daclatasvir, a Direct-Acting Antiviral (DAA), is an OCT2 inhibitor. Our study aimed to assess the potential interaction of daclatasvir with metformin pharmacokinetics and pharmacodynamics at two metformin doses. T...
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| Format: | Book |
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Ain Shams University,
2022-12-01T00:00:00Z.
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Internet
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A1234.567 |
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