Structural Optimization of Carboxy-Terminal Phenylalanine-Modified Dendrimers for T-Cell Association and Model Drug Loading

• Главные авторы: Hiroya Shiba (Автор), Tomoka Hirose (Автор), Akinobu Sakai (Автор), Ikuhiko Nakase (Автор), Akikazu Matsumoto (Автор), Chie Kojima (Автор)
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• Опубликовано: MDPI AG, 2024-05-01T00:00:00Z.
• Предметы: article
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Dendrimers are potent nanocarriers in drug delivery systems because their structure can be precisely controlled. We previously reported that polyamidoamine (PAMAM) dendrimers that were modified with 1,2-cyclohexanedicarboxylic acid (CHex) and phenylalanine (Phe), PAMAM-CHex-Phe, exhibited an effecti...