Ginkgo biloba Extract Inhibits Astrocytic Lipocalin-2 Expression and Alleviates Neuroinflammatory Injury via the JAK2/STAT3 Pathway After Ischemic Brain Stroke

• Main Authors: Yehao Zhang (Author), Jianxun Liu (Author), Bin Yang (Author), Yongqiu Zheng (Author), Mingjiang Yao (Author), Mingqian Sun (Author), Li Xu (Author), Chengren Lin (Author), Dennis Chang (Author), Fangze Tian (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Astrogliosis has the potential to lead to harmful effects, namely, neuroinflammation, and to interfere with synapse sprouting. Previous studies have suggested that Lipocalin-2 (LCN2) acts as a key target in regulating the reaction of astrocytes. However, the underlying molecular mechanis...